Northern RNA and ��Ӱ�� Announce Multi-year Agreement to Provide Essential Raw Materials and GMP Manufacturing in Support of ��Ӱ�� mRNA COVID-19 Vaccine Candidate, PTX-COVID19-B

Calgary, AB – Sept. 14, 2021 - and ��Ӱ�� today announced a multi-year agreement for Northern RNA to provide Plasmid DNA, mRNA Cap Analogs and Good Manufacturing Practices (GMP) certified manufacturing to support ��Ӱ��’s COVID-19 messenger RNA (mRNA) vaccine development and manufacturing requirements. The value of the agreement signed between Northern RNA and ��Ӱ�� is in excess of $15 million dollars and represents a continued joint commitment to bring mRNA-based vaccines to global markets.

“Northern RNA will provide leading-edge manufacturing of two key building blocks for the COVID-19 vaccine, including Cap Analogs and Plasmid DNA, essential raw materials needed to produce messenger RNA. We are very pleased to be able to support ��Ӱ�� with our proven manufacturing capabilities" said Brad Stevens, President and CEO, Northern RNA.

Covid-19 is a global challenge that has impacted us all. ��Ӱ�� provides vaccine solutions to help now, and in the future.

“We hold deep expertise in the science of mRNA and that experience has motivated us to work across the globe to supply a safe and effective Covid-19 vaccine with a focus on under-served markets,” said Brad Sorensen, CEO of ��Ӱ��.

Proudly Canadian, both Northern RNA and ��Ӱ�� appreciate the opportunity to bring vaccine solutions to global markets.

��Ӱ�� Northern RNA

Based in Calgary, Alberta Canada, Northern RNA is a world-class, customer-focused, end-to-end supplier of nucleic acid products such as mRNA and DNA. We develop in a state-of-the-art bioprocessing facility and deploy using proprietary manufacturing approaches and chemical process technologies. For more information, visit northernrna.com

��Ӱ�� Ӱ��

��Ӱ�� is Canada's leading mRNA vaccine company, with operations in Calgary, Alberta and Toronto, Ontario. In response to a worldwide need for a COVID-19 vaccine, ��Ӱ�� has expanded its focus beyond oncology and devoted its energy and resources to develop a mRNA vaccine for COVID-19. ��Ӱ�� is focused on serving the needs of Canada, and other countries that may be underserved by large pharma programs. For more information, please visit www.providencetherapeutics.com

Northern RNA Forward Looking Statement:

This press release contains forward-looking statements within the meaning of applicable securities laws including regarding Northern RNA’s manufacturing of raw materials for mRNA-based vaccines. The forward-looking statements in this press release are neither promises nor guarantees, and you should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond Northern RNA’s control, and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements. These risks, uncertainties, and other factors include, among others: potential adverse impacts due to the global COVID-19 pandemic such as delays in regulatory review, manufacturing and supply chain interruptions, and disruption of the global economy; and the fact that the mRNA manufacturing process in use by Northern RNA is still being developed and implemented. Except as required by law, Northern RNA disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this press release in the event of new information, future developments or otherwise. These forward-looking statements are based on Northern RNA’s current expectations and speak only as of the date hereof.

��Ӱ�� Forward Looking Statement:

This press release contains forward-looking statements within the meaning of applicable securities laws including regarding the ��Ӱ��'s development of a potential vaccine against COVID-19. The forward-looking statements in this press release are neither promises nor guarantees, and you should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond ��Ӱ��'s control, and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements. These risks, uncertainties, and other factors include, among others: the fact that the safety and efficacy of PTX-COVID19-B has not yet been established; potential adverse impacts due to the global COVID-19 pandemic such as delays in regulatory review, manufacturing and supply chain interruptions, adverse effects on healthcare systems and disruption of the global economy; the fact that there are a limited number of commercial products utilizing mRNA technology approved for use; and the fact that the mRNA technology in use by ��Ӱ�� is still being developed and implemented. Except as required by law, ��Ӱ�� disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this press release in the event of new information, future developments or otherwise. These forward-looking statements are based on ��Ӱ��'s current expectations and speak only as of the date hereof.

Northern RNA Media Contact:

Carissa Vescio
Investor Relations & Media
Northern RNA Inc.
(403) 701-0894

��Ӱ�� Contacts:

Neil Forester
President, The Substance Group
(416) 722-3793

Noy Wong
Investor Relations & Communications
��Ӱ�� Holdings Inc.

��Ӱ��

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